DJ Morgan,aa Specialist Registrar, Stranmillis, Belfast, IrelandDJ Morgan, Specialist Registrar, 1 Penge Gardens, Stranmillis, Belfast BT9 5GA, Ireland. Email drdavidjmorgan@yahoo.co.uk DC Hunter,b b Royal Jubilee Maternity Service, Belfast, Ireland G McCracken,c c Belfast City Hospital, Belfast, Ireland HR McClelland,c c Belfast City Hospital, Belfast, Ireland JH Price,c c Belfast City Hospital, Belfast, Ireland SP Dobbsc c Belfast City Hospital, Belfast, Irelanda Specialist Registrar, Stranmillis, Belfast, Ireland b Royal Jubilee Maternity Service, Belfast, Ireland c Belfast City Hospital, Belfast, Ireland
DJ Morgan, Specialist Registrar, 1 Penge Gardens, Stranmillis, Belfast BT9 5GA, Ireland. Email drdavidjmorgan@yahoo.co.uk
Abstract
Objective To compare a new surgical approach, laparoscopically assisted radical vaginal hysterectomy (LARVH) with open radical hysterectomy in women with cervical cancer. Can selected women benefit from the minimally invasive approach without compromising safety (recurrence rate) and morbidity (complications)?
Design Retrospective case control study.
Setting A tertiary referral unit for gynaecological malignancies.
Population Thirty women undergoing LARVH were included and compared with 30 women undergoing open radical surgery. The control group was matched for age, body mass index and disease stage.
Methods Retrospective collection of data from patient files and follow up.
Main outcome measures Recurrence rate, complication rate, hospital stay, nodal counts, blood loss, operating time.
Results Recurrence rates were equal (6.7%). There was one death, in the LARVH group. Follow up was mean 31 months in the LARVH group and 30.9 months in the open group. Blood loss as measured by mean drop in haemoglobin was greater in the open group (2.03 versus 3.01 g/dl, P = 0.02). Transfusions were given in 40% of women in the open group and 16.7% in the LARVH group. Hospital stay was significantly less in the LARVH group (5.9 versus 7.8 nights, P = 0.003). Mean operating time was longer in the LARVH group (131 versus 187 minutes P = 0.0001). Mean nodal counts did not differ significantly (17.4 in open vs 14.8 in LARVH, P > 0.05). There were seven perioperative complications in the open group and four in the LARVH group. There have been two recurrences in each group (6.67%) at mean follow up of 31 (LARVH) and 30.9 (open) months.
Conclusions The first 30 LARVH procedures performed in this unit are comparable in terms of safety (recurrence rate and complication rate) and economic factors (shorter hospital stay mitigating longer operating time). Further development of this technique is warranted.
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assisted radical vaginal hysterectomy for cervical carcinoma safe? A case control study with follow up
腔镜辅助阴道子宫根治切除术治疗宫颈癌安全吗? 一项随访对照病例研究
DJ Morgan,aa Specialist Registrar, Stranmillis, Belfast, IrelandDJ Morgan, Specialist Registrar, 1 Penge Gardens, Stranmillis, Belfast BT9 5GA, Ireland. Email drdavidjmorgan@yahoo.co.uk DC Hunter,b b Royal Jubilee Maternity Service, Belfast, Ireland G McCracken,c c Belfast City Hospital, Belfast, Ireland HR McClelland,c c Belfast City Hospital, Belfast, Ireland JH Price,c c Belfast City Hospital, Belfast, Ireland SP Dobbsc c Belfast City Hospital, Belfast, Irelanda Specialist Registrar, Stranmillis, Belfast, Ireland b Royal Jubilee Maternity Service, Belfast, Ireland c Belfast City Hospital, Belfast, Ireland
DJ Morgan, Specialist Registrar, 1 Penge Gardens, Stranmillis, Belfast BT9 5GA, Ireland. Email drdavidjmorgan@yahoo.co.uk
DJ Morgan,aa，专科注册医师， Stranmillis，爱尔兰贝尔法斯特。DJ Morgan，专科注册医师，1 Penge 花园，Stranmillis，BT9 5GA，爱尔兰贝尔法斯特，电子邮件 drdavidjmorgan@yahoo.co.uk DC Hunter,b b 皇家Jubilee妇产科中心， 贝尔法斯特, 爱尔兰 G McCracken,c c爱尔兰贝尔法斯特市医院， HR McClelland，c c 爱尔兰贝尔法斯特市医院，JH Price，c c 爱尔兰贝尔法斯特市医院，SP Dobbsc c 爱尔兰贝尔法斯特市医院，注册专科医师，Stranmillis，爱尔兰贝尔法斯特， b Royal Jubilee Maternity Service，爱尔兰贝尔法斯特， c 贝尔法斯特 City Hospital， 爱尔兰贝尔法斯特，
DJ Morgan，专科注册医师，1 Penge 公园，Stranmillis，贝尔法斯特 BT9 5GA，爱尔兰，电子邮件 drdavidjmorgan@yahoo.co.uk
Abstract
Objective To compare a new surgical approach, laparoscopically assisted radical vaginal hysterectomy (LARVH) with open radical hysterectomy in women with cervical cancer. Can selected women benefit from the minimally invasive approach without compromising safety (recurrence rate) and morbidity (complications)?
摘要
目的：比较一种新的手术方法，用开放性子宫根治方法的腹腔镜辅助根治性子宫切除术LARVH)治疗子宫颈癌患者。经由该方法选择的妇女能受益于微创的办法，而无安全损害(复发率)和发病率(并发症)？
Design Retrospective case control study.
设计回顾性病例对照研究.
Setting A tertiary referral unit for gynaecological malignancies.
设置：为妇科肿瘤设立一个第三位的参照组
Population Thirty women undergoing LARVH were included and compared with 30 women undergoing open radical surgery. The control group was matched for age, body mass index and disease stage.
总体：有30例接受LARVH 的妇女和30例接受开放性根治手术的对照组妇女。对照组妇女在年龄，体重指数和疾病的阶段均匹配。
Methods Retrospective collection of data from patient files and follow up.
方法：对病人资料和随访信息的回顾性整理.
Main outcome measures Recurrence rate, complication rate, hospital stay, nodal counts, blood loss, operating time.
主要测量结果：疾病的复发率，并发症发病率，住院时间，淋巴结节计数，出血量，手术时间。
Results Recurrence rates were equal (6.7%). There was one death, in the LARVH group. Follow up was mean 31 months in the LARVH group and 30.9 months in the open group. Blood loss as measured by mean drop in haemoglobin was greater in the open group (2.03 versus 3.01 g/dl, P = 0.02). Transfusions were given in 40% of women in the open group and 16.7% in the LARVH group. Hospital stay was significantly less in the LARVH group (5.9 versus 7.8 nights, P = 0.003). Mean operating time was longer in the LARVH group (131 versus 187 minutes P = 0.0001). Mean nodal counts did not differ significantly (17.4 in open vs 14.8 in LARVH, P > 0.05). There were seven perioperative complications in the open group and four in the LARVH group. There have been two recurrences in each group (6.67%) at mean follow up of 31 (LARVH) and 30.9 (open) months.
结果：复发率分别相等为(6.7%)。在LARVH组有一例死亡。LARVH组和开放组随访平均时间为31个月和30.9个月。用血红蛋白平均下降值测量出血量，开放组数值较大 (2.03比3.01 g/d， p=0.02)。开放组中40%的妇女有输血，LARVH组为16.7%。住院时间，LARVH 组明显减少(5.9比7.8夜，p=0.003)。LARVH组平均手术时间较长(131比187分钟，p=0.0001)。 平均淋巴结节计数无明显差异(17.4开放组比14.8 LARVH 组，p>0.05)。共有七个并发症手术期并发症在公开组，LARVH组有四个。 已有两次复发每一组(6.67%),在平均随访31(LARVH组)和30.9(开放组)间，每组有两例复发(6.67%)
Conclusions The first 30 LARVH procedures performed in this unit are comparable in terms of safety (recurrence rate and complication rate) and economic factors (shorter hospital stay mitigating longer operating time). Further development of this technique is warranted.
结论：在这个测试单元中，首次接收LARVH的30例妇女，在以安全(复发率及并发症率)和经济因素(缩短住院时间及减少较长的手术时间)方式比较上是合格的。因此进一步发展这一技术是值得的。
编译后：约733个字
来自爱尔兰贝尔法斯特的DJ Morgan等研究者，利用回顾性病例对照研究，比较一种新的手术方法，用开放性子宫根治方法的腹腔镜辅助根治性子宫切除术LARVH)治疗子宫颈癌患者。经由该方法选择的妇女能受益于微创的办法，而无安全损害(复发率)和发病率(并发症)？从而为妇科肿瘤设立一个第三位的参照组。
在该研究群体中，有30例接受LARVH 的妇女和30例接受开放性根治手术的对照组妇女。对照组妇女在年龄，体重指数和疾病的阶段均匹配。经对病人资料和随访信息的回顾性整理，得出以下主要测量结果：疾病的复发率，并发症发病率，住院时间，结节计数，出血量，手术时间。
结果显示：复发率分别相等为(6.7%)。在LARVH组有一例死亡。LARVH组和开放组随访平均时间为31个月和30.9个月。用血红蛋白平均下降值测量出血量，开放组数值较大 (2.03比3.01 g/d， p=0.02)。开放组中40%的妇女有输血，LARVH组为16.7%。住院时间，LARVH 组明显减少(5.9比7.8夜，p=0.003)。LARVH组平均手术时间较长(131比187分钟，p=0.0001)。 平均淋巴结节计数无明显差异(17.4开放组比14.8 LARVH 组，p>0.05)。共有七个并发症手术期并发症在公开组，LARVH组有四个。 已有两次复发每一组(6.67%),在平均随访31(LARVH组)和30.9(开放组)间，每组有两例复发(6.67%)。
综上，研究者提出以下结论：在这个测试单元中，首次接受LARVH治疗的30例妇女，在以安全因素(复发率及并发症率)和经济因素(缩短住院时间及减少较长的手术时间)方式比较上是合格的。因此值得进一步发展这一技术的。
liuzeyi2002 wrote:
assisted radical vaginal hysterectomy for cervical carcinoma safe? A case control study with follow up
腔镜辅助阴道根治性子宫切除术治疗宫颈癌安全吗? 一项随访对照病例研究
DJ Morgan,aa Specialist Registrar, Stranmillis, Belfast, IrelandDJ Morgan, Specialist Registrar, 1 Penge Gardens, Stranmillis, Belfast BT9 5GA, Ireland. Email drdavidjmorgan@yahoo.co.uk DC Hunter,b b Royal Jubilee Maternity Service, Belfast, Ireland G McCracken,c c Belfast City Hospital, Belfast, Ireland HR McClelland,c c Belfast City Hospital, Belfast, Ireland JH Price,c c Belfast City Hospital, Belfast, Ireland SP Dobbsc c Belfast City Hospital, Belfast, Irelanda Specialist Registrar, Stranmillis, Belfast, Ireland b Royal Jubilee Maternity Service, Belfast, Ireland c Belfast City Hospital, Belfast, Ireland
DJ Morgan, Specialist Registrar, 1 Penge Gardens, Stranmillis, Belfast BT9 5GA, Ireland. Email drdavidjmorgan@yahoo.co.uk
DJ Morgan,aa，专科注册医师， Stranmillis，爱尔兰贝尔法斯特。DJ Morgan，专科注册医师，1 Penge 花园，Stranmillis，BT9 5GA，爱尔兰贝尔法斯特，电子邮件 drdavidjmorgan@yahoo.co.uk DC Hunter,b b 皇家Jubilee妇产科中心， 贝尔法斯特, 爱尔兰 G McCracken,c c爱尔兰贝尔法斯特市医院， HR McClelland，c c 爱尔兰贝尔法斯特市医院，JH Price，c c 爱尔兰贝尔法斯特市医院，SP Dobbsc c 爱尔兰贝尔法斯特市医院，注册专科医师，Stranmillis，爱尔兰贝尔法斯特， b Royal Jubilee Maternity Service，爱尔兰贝尔法斯特， c 贝尔法斯特 City Hospital， 爱尔兰贝尔法斯特，
DJ Morgan，专科注册医师，1 Penge 公园，Stranmillis，贝尔法斯特 BT9 5GA，爱尔兰，电子邮件 drdavidjmorgan@yahoo.co.uk
Abstract
Objective To compare a new surgical approach, laparoscopically assisted radical vaginal hysterectomy (LARVH) with open radical hysterectomy in women with cervical cancer. Can selected women benefit from the minimally invasive approach without compromising safety (recurrence rate) and morbidity (complications)?
摘要
目的：将一种新的手术方法，即腹腔镜辅助根治性子宫切除术LARVH)与开放式根治性子宫切除术治疗子宫颈癌患者相比较。[color=red]挑选[/color]的妇女能受益于微创的办法而不危及安全(复发率)和发病率(并发症)吗？
Design Retrospective case control study.
设计回顾性病例对照研究.
Setting A tertiary referral unit for gynaecological malignancies.
实施：一个妇科肿瘤三级转诊单位
Population Thirty women undergoing LARVH were included and compared with 30 women undergoing open radical surgery. The control group was matched for age, body mass index and disease stage.
总体：有30例接受LARVH 的妇女和30例接受开放性根治手术的对照组妇女。对照组妇女在年龄，体重指数和疾病的期别均匹配。
Methods Retrospective collection of data from patient files and follow up.
方法：对病人资料和随访信息的回顾性整理.
Main outcome measures Recurrence rate, complication rate, hospital stay, nodal counts, blood loss, operating time.
主要测量结果：疾病的复发率，并发症发病率，住院时间，淋巴结计数，出血量，手术时间。
Results Recurrence rates were equal (6.7%). There was one death, in the LARVH group. Follow up was mean 31 months in the LARVH group and 30.9 months in the open group. Blood loss as measured by mean drop in haemoglobin was greater in the open group (2.03 versus 3.01 g/dl, P = 0.02). Transfusions were given in 40% of women in the open group and 16.7% in the LARVH group. Hospital stay was significantly less in the LARVH group (5.9 versus 7.8 nights, P = 0.003). Mean operating time was longer in the LARVH group (131 versus 187 minutes P = 0.0001). Mean nodal counts did not differ significantly (17.4 in open vs 14.8 in LARVH, P > 0.05). There were seven perioperative complications in the open group and four in the LARVH group. There have been two recurrences in each group (6.67%) at mean follow up of 31 (LARVH) and 30.9 (open) months.
结果：复发率分别相等为(6.7%)。在LARVH组有一例死亡。LARVH组和开放组随访平均时间为31个月和30.9个月。用血红蛋白平均下降值测量出血量，开放组数值较大 (2.03比3.01 g/d， p=0.02)。开放组中40%的妇女有输血，LARVH组为16.7%。住院时间，LARVH 组明显减少(5.9比7.8夜，p=0.003)。LARVH组平均手术时间较长(131比187分钟，p=0.0001)。 平均淋巴结计数无明显差异(17.4开放组比14.8 LARVH 组，p>0.05)。共有七个并发症手术期并发症在公开组，LARVH组有四个。 已有两次复发每一组(6.67%),在平均随访31(LARVH组)和30.9(开放组)间，每组有两例复发(6.67%)
Conclusions The first 30 LARVH procedures performed in this unit are comparable in terms of safety (recurrence rate and complication rate) and economic factors (shorter hospital stay mitigating longer operating time). Further development of this technique is warranted.
结论：在这个测试单元中，首次接收LARVH的30例妇女，在以安全(复发率及并发症率)和经济因素(缩短住院时间及减少较长的手术时间)方式比较上是合格的。因此进一步发展这一技术是值得的。
编译后：约733个字腔镜辅助阴道子宫切除术治疗宫颈癌安全吗? 一项随访对照病例研究
来自爱尔兰贝尔法斯特的DJ Morgan等研究者，利用回顾性病例对照研究，比较一种新的手术方法，用开放性子宫根治方法的腹腔镜辅助根治性子宫切除术LARVH)治疗子宫颈癌患者。经由该方法选择的妇女能受益于微创的办法，而无安全损害(复发率)和发病率(并发症)？从而为妇科肿瘤设立一个第三位的参照组。
在该研究群体中，有30例接受LARVH 的妇女和30例接受开放性根治手术的对照组妇女。对照组妇女在年龄，体重指数和疾病的阶段均匹配。经对病人资料和随访信息的回顾性整理，得出以下主要测量结果：疾病的复发率，并发症发病率，住院时间，结节计数，出血量，手术时间。
结果显示：复发率分别相等为(6.7%)。在LARVH组有一例死亡。LARVH组和开放组随访平均时间为31个月和30.9个月。用血红蛋白平均下降值测量出血量，开放组数值较大 (2.03比3.01 g/d， p=0.02)。开放组中40%的妇女有输血，LARVH组为16.7%。住院时间，LARVH 组明显减少(5.9比7.8夜，p=0.003)。LARVH组平均手术时间较长(131比187分钟，p=0.0001)。 平均结节计数无明显差异(17.4开放组比14.8 LARVH 组，p>0.05)。共有七个并发症手术期并发症在公开组，LARVH组有四个。 已有两次复发每一组(6.67%),在平均随访31(LARVH组)和30.9(开放组)间，每组有两例复发(6.67%)。
综上，研究者提出以下结论：在这个测试单元中，首次接受LARVH治疗的30例妇女，在以安全因素(复发率及并发症率)和经济因素(缩短住院时间及减少较长的手术时间)方式比较上是合格的。因此值得进一步发展这一技术的。
翻译得不错，红色部分是个人意见，供参考。
谢谢moro战友，你这种负责任的精神很好，早上不到6点来改错，谢谢！