Title：Occupational Risk Factors and Asthma among Health Care Professionals
Author：George L. Delclos, David Gimeno, Ahmed A. Arif
Resource: American Journal of Respiratory and Critical Care Medicine Vol 175. pp. 667-675, (2007)
Abstract:
Rationale: Recent U.S. data suggest an increased risk of work-related asthma among health care workers, yet only a few specific determinants have been elucidated.
Objectives: To evaluate associations of asthma prevalence with occupational exposures in a cross-sectional survey of health care professionals.
Methods: A detailed questionnaire was mailed to a random sample (n = 5,600) of all Texas physicians, nurses, respiratory therapists, and occupational therapists with active licenses in 2003. Information on asthma symptoms and nonoccupational asthma risk factors obtained from the questionnaire was linked to occupational exposures derived through an industry-specific job-exposure matrix.
Measurements: There were two a priori defined outcomes: (1) physician-diagnosed asthma with onset after entry into health care ("reported asthma") and (2) "bronchial hyperresponsiveness–related symptoms," defined through an 8-item symptom-based predictor.
Main Results: Overall response rate was 66%. The final study population consisted of 862 physicians, 941 nurses, 968 occupational therapists, and 879 respiratory therapists (n = 3,650). Reported asthma was associated with medical instrument cleaning (odds ratio [OR], 2.22; 95% confidence interval [CI], 1.34–3.67), general cleaning (OR, 2.02; 95% CI, 1.20–3.40), use of powdered latex gloves between 1992 and 2000 (OR, 2.17; 95% CI, 1.27–3.73), and administration of aerosolized medications (OR, 1.72; 95% CI, 1.05–2.83). The risk associated with latex glove use was not apparent after 2000. Bronchial hyperresponsiveness–related symptoms were associated with general cleaning (OR, 1.63; 95% CI, 1.21–2.19), aerosolized medication administration (OR, 1.40; 95% CI, 1.06–1.84), use of adhesives on patients (OR, 1.65; 95% CI, 1.22–2.24), and exposure to a chemical spill (OR, 2.02; 95% CI, 1.28–3.21).
Conclusions: The contribution of occupational exposures to asthma in health care professionals is not trivial, meriting both implementation of appropriate controls and further study.
Key Words: work-related asthma • health care workers
AT A GLANCE COMMENTARY
Scientific Knowledge on the Subject
Data suggest an increased risk of work-related asthma in U.S. health care workers, yet few specific determinants have been elucidated. Confirmation and estimation of risk in population-based studies has been inconsistent and more problematic.
What This Study Adds to the Field
Occupational exposures are important contributors to asthma in health care providers.
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Title：Occupational Risk Factors and Asthma among Health Care Professionals
健康保健人士的职业风险因素与哮喘Author：George L. Delclos, David Gimeno, Ahmed A. Arif
Resource: American Journal of Respiratory and Critical Care Medicine Vol 175. pp. 667-675, (2007)
来源：美国呼吸与急症护理医学杂志，175卷，667-675，2007年
Abstract:
Rationale: Recent U.S. data suggest an increased risk of work-related asthma among health care workers, yet only a few specific determinants have been elucidated.
摘要：
原理：美国最近有数据显示，健康保健人员中间增加了与职业有关的哮喘的患病率，然而只阐明了少数特定的决定因素。
Objectives: To evaluate associations of asthma prevalence with occupational exposures in a cross-sectional survey of health care professionals.
目的：通过对卫生保健专业人才进行有代表性的调查，评估哮喘流行与职业暴露之间的关系。
Methods: A detailed questionnaire was mailed to a random sample (n = 5,600) of all Texas physicians, nurses, respiratory therapists, and occupational therapists with active licenses in 2003. Information on asthma symptoms and no noccupational asthma risk factors obtained from the questionnaire was linked to occupational exposures derived through an industry-specific job-exposure matrix.
方法：2003年一份详细的问卷调查表被邮寄发放进行随机抽样调查，调查人员包括得克萨斯州的医生、护士、呼吸治疗师、2003年有职业许可证的职业治疗师。从工业化的特殊的职业暴露归纳出，调查问卷显示的哮喘症状的信息和非职业性哮喘风险因素与职业暴露是有关的。
Measurements: There were two a priori defined outcomes: (1) physician-diagnosed asthma with onset after entry into health care ("reported asthma") and (2) "bronchial hyperresponsiveness–related symptoms," defined through an 8-item symptom-based predictor.
诊断标准：有两个首要的确定结果：1.从事健康保健工作后， 出现症状并被医生确诊的哮喘（报告哮喘）和2.气管高反应性症状，通过8个条款基于症状的预测来定义。
Main Results: Overall response rate was 66%. The final study population consisted of 862 physicians, 941 nurses, 968 occupational therapists, and 879 respiratory therapists (n = 3,650). Reported asthma was associated with medical instrument cleaning (odds ratio [OR], 2.22; 95% confidence interval [CI], 1.34–3.67), general cleaning (OR, 2.02; 95% CI, 1.20–3.40), use of powdered latex gloves between 1992 and 2000 (OR, 2.17; 95% CI, 1.27–3.73), and administration of aerosolized medications (OR, 1.72; 95% CI, 1.05–2.83). The risk associated with latex glove use was not apparent after 2000. Bronchial hyperresponsiveness–related symptoms were associated with general cleaning (OR, 1.63; 95% CI, 1.21–2.19), aerosolized medication administration (OR, 1.40; 95% CI, 1.06–1.84), use of adhesives on patients (OR, 1.65; 95% CI, 1.22–2.24), and exposure to a chemical spill (OR, 2.02; 95% CI, 1.28–3.21).
主要结果：所有的回答率为66%。最终的被研究人群包括862位医生、941位护士、968位职业治疗师和879位呼吸治疗师（总人数为3，650）报告称，与医疗器械清洗有关的哮喘（优势比：2.22；95%可信区间1.34-3.67）；一般清洗有关的哮喘（优势比：2.02；95%可信区间1.20-3.40）；于1992-2000年间使用带有粉末乳胶手套有关的哮喘（优势比：2.17；95%可信区间1.27-3.73）；雾化器使用实施者（优势比：1.72；95%可信区间1.05-2.83）。2000年以后与手套使用有关的风险并不是非常名。与一般清洗有关的支气管高反应性症状(优势比, 1.63； 95%可信区间：1.21–2.19)，与使用雾化器治疗有关的支气管高反应性症状(优势比, 1.40； 95%可信区间, 1.06–1.84)，与对病人使用粘合剂有关的支气管高反应性症状(优势比, 1.65；95%可信区间：1.22–2.24)和与暴露于化学药品溢出有关的支气管高反应性症状(优势比, 2.02；95%可信区间： 1.28–3.21).
Conclusions: The contribution of occupational exposures to asthma in health care professionals is not trivial, meriting both implementation of appropriate controls and further study.
结论：健康保健专业人员人群患上哮喘，职业暴露的因素不是轻微的，认识到这一点对于完善适当的控制和进一步的研究都是有好处的。
Key Words: work-related asthma • health care workers
关键词：职业暴露哮喘；健康保健人员
AT A GLANCE COMMENTARY
Scientific Knowledge on the Subject
Data suggest an increased risk of work-related asthma in U.S. health care workers, yet few specific determinants have been elucidated. Confirmation and estimation of risk in population-based studies has been inconsistent and more problematic.
数据显示在美国健康监护人员患职业性哮喘病的风险增加了，然而只有少数决定因素被阐明。基于人群的研究，对于风险的认证和预测还存在矛盾和很多的疑问。
What This Study Adds to the Field
Occupational exposures are important contributors to asthma in health care providers.
职业暴露是健康监护人员患哮喘病的重要因素。
以上是我的作业，标蓝色的是自己是在翻译不好的，请大家帮帮忙，看看应该怎么翻译，
下面是对文章的编译:
Title：Occupational Risk Factors and Asthma among Health Care Professionals
健康保健人士的职业风险因素与哮喘
来源：美国呼吸与急症护理医学杂志，175卷，667-675，2007年
摘要：
原理：美国最近有数据显示，健康保健人员中间增加了与职业有关的哮喘的患病率，然而只阐明了少数特定的决定因素。
目的：通过对卫生保健专业人才进行有代表性的调查，评估哮喘流行与职业暴露之间的关系。
方法：2003年一份详细的问卷调查表被邮寄发放进行随机抽样调查，调查人员包括得克萨斯州的医生、护士、呼吸治疗师、有职业许可证的职业治疗师。从工业的特殊的职业暴露归纳出，调查问卷显示的哮喘症状和非职业性哮喘风险因素的信息与职业暴露是有关的。
诊断标准：有两个首要的确定结果：1.从事健康保健工作后， 出现症状并被医生确诊的哮喘（报告哮喘）和2.气管高反应性症状，通过8条基于症状的预测来定义。
主要结果：调查问卷的回复率为66%。最终的被研究人群包括862位医生、941位护士、968位职业治疗师和879位呼吸治疗师（总人数为3，650）。报告称，与医疗器械清洗有关的哮喘（优势比：2.22；95%可信区间1.34-3.67）；一般清洗有关的哮喘（优势比：2.02；95%可信区间1.20-3.40）；于1992-2000年间使用带有粉末乳胶手套有关的哮喘（优势比：2.17；95%可信区间1.27-3.73）；雾化器使用实施者（优势比：1.72；95%可信区间1.05-2.83）。2000年以后与手套使用有关的风险并不是非常名。与一般清洗有关的支气管高反应性症状(优势比, 1.63； 95%可信区间：1.21–2.19)，与使用雾化器治疗有关的支气管高反应性症状(优势比, 1.40； 95%可信区间, 1.06–1.84)，与对病人使用粘合剂有关的支气管高反应性症状(优势比, 1.65；95%可信区间：1.22–2.24)和与暴露于化学药品溢出有关的支气管高反应性症状(优势比, 2.02；95%可信区间： 1.28–3.21).
结论：健康保健专业人员人群患上哮喘，职业暴露的因素不是轻微的，认识到这一点对于完善适当的控制和进一步的研究都是有好处的。
关键词：职业暴露哮喘；健康保健人员
数据显示在美国健康监护人员患职业性哮喘病的风险增加了，然而只有少数决定因素被阐明。基于人群的研究，对于风险的认证和预测还存在矛盾和很多的疑问。
职业暴露是健康监护人员患哮喘病的重要因素。
我试一下
Information on asthma symptoms and no noccupational asthma risk factors obtained from the questionnaire was linked to occupational exposures derived through an industry-specific job-exposure matrix
根据调查表得到哮喘症状的信息和非职业哮喘危险因素，用特殊行业的工种接触浓度矩阵可归纳出，其与职业暴露是相关的。
谢谢天狼王！
本篇难度较大，这些资料国内较少，再提点建议：
健康保健人员中间增加了与职业有关的哮喘的患病率，然而只阐明了少数特定的决定因素。改为：
健康保健人员中间与职业有关的哮喘的患病率增加，然而只有少数特定的决定因素被阐明。
与医疗器械清洗 一般清洗 改为： 与医疗器械清洁 一般清洁
雾化器使用实施者 改为： 实施雾化给药
最终的被研究人群包括862位医生、941位护士、968位职业治疗师和879位呼吸治疗师（总人数为3，650）报告称，与医疗器械清洗有关的哮喘（优势比：2.22；95%可信区间1.34-3.67）；改为：
最终的被研究人群包括862位医生、941位护士、968位职业治疗师和879位呼吸治疗师（n = 3，650）。报告的哮喘与下列因素有关：医疗器械清洗（优势比：2.22；95%可信区间1.34-3.67）；
所有的回答率为66% 改为： 总应答率为66%
谢谢jiaxing斑竹! 谢谢天狼王!
非常感谢你们的修改和提出的意见.我翻译这篇文章的时候,也是感到有些地方非常不通顺,谢谢!
