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Error rate of N.L. cancer tests alarms advocates
N.L.肿瘤检测的错误率对其拥护者拉响了警报
Last Updated: Tuesday, May 15, 2007 | 6:35 AM ET
CBC News
Faulty hormone receptor tests disqualified scores of women in Newfoundland and Labrador from receiving potentially life-saving treatment for breast cancer, court documents show.
法院文件显示，纽芬兰和拉布拉多的数十名妇女因不完善的激素受体测试而丧失了获得可能的针对乳腺癌的挽救生命性的治疗的资格。
Eastern Health announced in 2005 it was retesting samples from hundreds of women.
(CBC) The documents also show the error rate for a controversial series of tests completed over an eight-year period is much higher than expected.
东部卫生组织宣布：2005年他们一直在重测数百名妇女的样本。(CBC)文件还显示8年内完成的具争议性的一系列试验的误差率远远高于预期。
For almost two years, the Eastern Health regional authority has been grappling with erroneous hormone receptor testing. A class action lawsuit has been filed over the tests, which have involved hundreds of women.
近两年,东部卫生组织的区域主管一直在处理有误的激素受体测试.一项涉及数百名妇女的集体诉讼已申请了测试。
When testing began in 2005, Eastern Health predicted that about 10 per cent of the tests would be wrong. But an affidavit filed by Eastern Health as a response to the lawsuit shows the error rate is actually much higher.
2005年试验刚刚开始的时候,东部卫生组织预言约有百分之十的试验（结果）是错误的。但在东部卫生组织回应这场官司的宣誓书中，误差率实际上远远高于预期。
Of 763 patients who tested negative, 317 turned out to have been given wrong results.
763名阴性患者中，317名患者的结果却是错误的。
"It looks like there was upwards of 42 per cent of the tests results were actually wrong, and that's a pretty startling number," said Peter Dawe, executive director of the Canadian Cancer Society.
加拿大癌症协会的执行主任Peter Dawe说:"结果显示，高达42%的测试结果实际上是错的，这是一个相当惊人的数字。"
"My initial reaction was that I was surprised that the numbers were so high."
"我最初的反应是我对于如此高的数量觉得很惊讶。"
Gerry Rogers said she was disturbed to learn of the error rate in hormone receptor tests.
(CBC) Dawe and other cancer advocates have been lobbying for more information about the hormone receptor tests since the summer of 2005, when Eastern Health arranged with Mount Sinai Hospital in Toronto to retest samples.
Gerry Rogers说,她为激素受体测试的误差率感到不安。(CBC)自2005年夏季以来，Dawe和其他癌症的倡导者一直游说更多的有关激素受体基因测试，而东部卫生组织正准备与多伦多的Mount Sinai医院重测样本.
According to a February 2007 affidavit signed by Heather Predham, assistant director of quality and risk management with Eastern Health, of the 317 patients with wrong results, 104 patients required a change in treatment.
根据2007年2月东部卫生组织质量和风险管理署副主任Heather Predham签署宣誓书,317名患者结果有误,104名患者需要改变治疗方案.
Of those, 96 were prescribed Tamoxifen, a drug therapy considered one of the best options for blocking the hormones that promote cancerous cell growth.
其中,96名患者正在服用三苯氧胺，这种药物治疗被认为是阻断促进癌细胞生长的激素的最佳方案之一。
Gerry Rogers, a St. John's filmmaker who is one of the more than 40 women involved in the class action suit, said she was deeply disturbed by the findings.
参加了集体诉讼的40多名妇女之一圣约翰电影导演Gerry Rogers说她为这个结果深感不安。
"When people are sick and you've had cancer, people are so afraid, you're just so afraid — you automatically think you're going to die," said Rogers.
"当人们生病，或有癌症时,人是如此害怕,你就这么害怕,你会不自觉的想到你会死," Rogers说。
"So you need to have faith and trust in the medical system, in your doctors, and I really have a lot of respect and trust in the doctors who have taken care of me. But it kind of shakes your foundation when you know it's still a bit of a crapshoot and then this stuff happens," she said.
她说"所以你必须对医疗制度和你的医生有信心与信任的,我真的对照顾我的医生充满尊敬和信赖。但当你知道它仍是投机取巧性的，你(信任)的根基就被摇动，然后这些事就发生了。"
Eastern Health is not commenting on the testing while the matter is in court. A judge is expected to decide later this month whether the class action lawsuit will proceed.
东部卫生组织并非是此案正在诉讼中时对其进行评论。本月晚些时候将决定这起集体诉讼是否继续进行。
Eastern Health is not releasing the results of tests that were redone for 176 patients who died since their original tests.
东部卫生组织并未公布初次测试后死亡的176名患者的重测结果。
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编译投稿：790字
N.L.肿瘤检测的错误率对其拥护者拉响了警报
【据CBC2007年5月15日的报道】法院的文件显示，纽芬兰和拉布拉多的数十名妇女因不完善的激素受体测试而丧失了获得可能的针对乳腺癌的挽救生命性治疗的资格。文件还显示8年内完成的具争议性的这一系列试验的误差率远远高于预期。近两年东部卫生组织区域专家一直在处理有误的激素受体测试，而一项涉及数百名妇女的集体诉讼已申请了该项测试。
东部卫生组织宣布：2005年他们一直在重测数百名妇女的样本。（注：我看了原文，此处为图片的下注，从文章的整体布局来说，调整到第二段比较合适。）2005年试验刚刚开始的时候,东部卫生组织预言约有百分之十的试验（结果）是错误的。但在东部卫生组织回应这场官司的宣誓书中，误差率实际上远远高于预期。
763名阴性患者中，317名患者的结果实际上是错误的。加拿大癌症协会的执行主任Peter Dawe说:“结果显示，高达42％的测试结果实际上是错的，这是一个相当惊人的数字。我最初的反应是对于如此高的数量感觉到很惊讶。”
自2005年夏季以来，Dawe和其他癌症的倡导者一直游说（应该获得）更多的有关激素受体基因测试的信息，而东部卫生组织正准备与多伦多的Mount Sinai医院重测样本。根据2007年2月东部卫生组织质量和风险管理署副主任Heather Predham签署宣誓书，317名患者结果有误，104名患者需要改变其治疗方案。其中，96名患者正在服用三苯氧胺，而这种药物治疗被认为是阻断促进癌细胞生长的激素的最佳方案之一。
参加了集体诉讼的40多名妇女之一圣约翰电影导演Gerry Rogers说她为这个结果深感不安。她说，"当人们生病，或有癌症时，人是如此害怕，你就这么害怕，你会不自觉的想到你会死。所以你必须对医疗制度和你的医生有信心与信任的,我真的对照顾我的医生充满尊敬和信赖。但当你知道它仍是投机取巧性的，你(信任)的根基就被摇动，然后这些事就发生了。”
东部卫生组织并非是此案正在诉讼中时对其进行评论。本月晚些时候将决定这起集体诉讼是否继续进行。但东部卫生组织并未公布初次测试后死亡的176名患者的重测结果。
